Diverse Bacterial Consortia in Medicinal Plants: An Ecological and Pharmacological Perspective
Keywords:
Medicinal plants, bioactive compounds, antimicrobial activity, new antimicrobials, challenges, future perspectivesAbstract
The escalating incidence of drug-resistant pathogens underscores the urgent necessity to discover and isolate novel bioactive compounds from medicinal plants, utilizing standardized, contemporary analytical procedures. Medicinal plant-derived compounds hold the promise of offering innovative strategies against pathogenic bacteria. This comprehensive review delves into the antimicrobial properties of components derived from plants, elucidates their potential mechanisms of action, and examines their chemical attributes. Emphasis is placed on the present challenges and future prospects in the realm of medicinal plant-derived antimicrobials.
Challenges inherent to medicinal plant extracts and their antimicrobial efficacy need to be addressed. The effectiveness of extraction methodologies is influenced by the specific plant species, leading to enhanced and selectively isolated compounds. Variability in the results of antimicrobial susceptibility tests for plant extracts can complicate the assessment of their antimicrobial activity. Furthermore, there exist a multitude of obstacles that must be surmounted to harness the full potential of plant extracts as sources of new antimicrobials, even as efforts are ongoing to augment the antimicrobial potential of chemical compounds. Research focusing on understanding the mechanisms of action, interactions with other substances, and the pharmacokinetic and pharmacodynamic profiles of medicinal plant extracts should be accorded high priority to establish their credentials as prospective antimicrobial agents.
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References
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